If the app needs TLS 1.0 enabled, change the settings and test the app. A reboot is not required.
Apps like Cofense and FS Pro 2020 runs on TLS 1.0.
HKEY_LOCAL_MACHINE\SYSTEM\CurrentControlSet\Control\SecurityProviders\SCHANNEL\Protocols\TLS 1.0\Client
Set these keys to the value below.
DisabledByDefault to 0
Enabled to 1